Fangming Xiao
Fangming Xiao
Professor
Office
Ag Biotech, Room 203
Phone
208-885-0120
Email
Mailing Address
Department of Plant Sciences
University of Idaho
875 Perimeter Drive MS 2333
Moscow, ID 83844-2333
Fangming is a plant molecular biologist studying molecular basis of plant-pathogen/nematode interactions, plant response to abiotic stress, and ubiquitination-mediated regulation of plant growth and development.
Courses
- PLSC 207: Introduction to Biotechnology
- PLSC 440: Advanced Laboratory Techniques
Languages other than English spoken
- Chinese
- Plant-pathogen/nematode interactions. Molecular basis of nematode parasitism: investigate how the nematode effector RHA1B (a ubiquitin ligase) manipulates host physiology to establish the feeding site (syncytium) and identify its putative host targets, particularly susceptibility genes, and generate resistance plants via loss of susceptibility using the CRISPR approach. Nematode-associated molecular pattern (NAMP)-mediated immune signaling and resistance: investigate the recognition of NAMP Ascaroside 18 (Ascr18) by host pattern recognition receptor (PRR) NILR1 and co-receptor BAK1 and consequent immune signal activation and transduction in Arabidopsis, potato and tomato. The Prf-mediated defense signaling in tomato: The NLR type Prf resistance protein confers resistance to Pseudomonas syringae pv. tomato (Pst) in tomato. We seek to determine the mechanistic basis by which Prf, upon activated by the recognition of avirulent effectors AvrPto and AvrPtoB, manipulates defense-related transcription factors towards resistance to Pst.
- Plant response to abiotic stress. The mechanistic basis by which NAC transcription factors regulate responses to abiotic stress (cold, drought and high salinity) — what are the direct target genes of NAC transcription factors and how they are regulated, particularly via ubiquitination, in response to stress and how to manipulate them towards improved tolerance to abiotic stress.
- ubiquitination-mediated regulation of growth and development in tomato — what are genes/signaling pathways mediated by two ubiquitin ligase/transcription factor-based regulatory modules (SINA1-BSD1 and SINA3-WOX14) and how they contribute to growth and development in tomato.
- Huang L, Yuan Y, Ramiez C, Zhao Z., Chen T., Griebel T., Kud J, Kuhl JC, Caplan A, Dandurand L-M, Xiao F* (2024) A receptor for dual ligands governs plant immunity and hormone response and is targeted by a nematode effector. Proceedings of the National Academy of Sciences. 2024 Oct 15;121(42): e2412016121. doi: 10.1073/pnas.2412016121. Epub 2024 Oct 10.
- Huang L, Yuan Y, Ramiez C, Xia C., Zhang C., Kud J, Kuhl JC, Caplan A, Dandurand L-M, Xiao F* (2024) The potato RNA metabolism machinery is targeted by the cyst nematode effector RHA1B for successful parasitism. The Plant Cell. 2024 Sep 26:koae264. doi: 10.1093/plcell/koae264. Online ahead of print. PMID: 39325717
- Yuan Y, Fan Y, Huang L, Lu H, Tan B, Ramirez C, Xia C, Niu X, Chen S, Gao M, Zhang C, Liu Y, Xiao F* (2024). The SINA1-BSD1 Module Regulates Vegetative Growth Involving Gibberellin Biosynthesis in Tomato. Advanced Science. 2024 Aug 27:e2400995. doi: 10.1002/advs.202400995. Online ahead of print. PMID: 39190572
- Huang L, Yuan Y, Lewis C, Kud J, Kuhl JC, Caplan A, Dandurand L-M, Zasada I, Xiao F* (2023). NILR1 perceives a nematode ascaroside triggering immune signaling and resistance. Current Biology. 2023 Sep 25;33(18):3992-3997.e3. doi: 10.1016/j.cub.2023.08.017. Epub 2023 Aug 28. PMID: 37643618
- Lu H, Niu X, Fan Y, Yuan Y, Huang L, Zhao B, Liu Y, Xiao F* (2023) The extensin protein SAE1 plays a role in leaf senescence and is targeted by the ubiquitin ligase SlSINA4 in tomato. Journal of Experimental Botany. 2023 Jun 27:erad 242. doi: 10.1093/jxb/erad242. Online ahead of print.PMID: 37368909
- Lu H, Fan Y, Yuan Y, Niu X, Zhao B, Liu Y, Xiao F* (2023) Tomato SlSTK is involved in glucose response and regulated by the ubiquitin ligase SlSINA4. Plant Science. 2023 Jun;331:111672. doi: 10.1016/j.plantsci.2023.111672. Epub 2023 Mar 13.PMID: 36921631
- Niu X, Lu H, Fan Y, Wang W, Yuan Y, Hawkins M, Zhang J, Ye Z, Miao M, Liu Y, Xiao F* (2022) Manipulation of the transcription factor SlNAC1 for improved tolerance to abiotic stress in tomato. Plant, Cell and Environment. 2022 Dec;45(12):3537-3550. doi: 10.1111/pce.14437. Epub 2022 Sep 30
- Fan Y, Niu X, Huang L, Gross R, Lu H, Hawkins M, Yuan Y, Miao M, Liu Y, Xiao F* (2020). A novel BSD domain-containing transcription factor controlling vegetative growth, leaf senescence and fruit quality in tomato. Journal of Experimental Botany. 2020 Aug 26:eraa393. doi: 10.1093/jxb/eraa393.
- Gross R, Zhang S, Wei L, Caplan A, Kuhl J, Dandurand L-M, Wang X, Xiao F* (2020). The Globodera pallida effector GpPDI1 is a functional thioredoxin and triggers defense-related cell death independent of its enzymatic activity. Phytopathology. 2020 Nov;110(11):1838-1844. doi: 10.1094/PHYTO-02-20-0038-R. Epub 2020 Sep 10.
- Zhang S, Li C, Ren H, Zhao T, Li Q, Wang S, Zhang Y, Xiao F*, Wang X* (2020). BAK1 mediates light Intensity to phosphorylate and activate catalases to regulate plant growth and development. International Journal of Molecular Sciences. 2020 Feb 20;21(4). pii: E1437. doi: 10.3390/ijms21041437.
- Kud J., Solo N, Caplan A, Kuhl JC, Dandurand L-M*, Xiao F* (2019). In situ hybridization of plant-parasitic nematode Globodera pallida juveniles to detect gene expression. Bio-protocol 9(18): e3372. DOI: 10.21769/BioProtoc.3372.
- Kud J., Wang W, Yuan Y, Caplan A, Kuhl JC, Dandurand L-M*, Xiao F* (2019). Functional characterization of RING-type E3 ubiquitin ligases in vitro and in planta. J Vis Exp. (154), e60533, doi:10.3791/60533 (2019).
- Kud J, Wang W, Gross R, Fan Y, Huang L, Yuan Y, Gray A, Duarte A, Kuhl JC, Caplan A, Goverse A, Liu Y, Dandurand LM*, Xiao F* (2019). The potato cyst nematode effector RHA1B is a ubiquitin ligase and uses two distinct mechanisms to suppress plant immune signaling. PLOS Pathogens. 2019 Apr 12;15(4):e1007720. doi: 10.1371/journal.ppat.1007720. eCollection 2019 Apr.